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SMi’s 5th Annual Conference
3D Cell Culture
February 09-10, 2022 | Conference
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3D Cell Culture has gained increasing momentum in the pharmaceutical industry over recent years, with the global 3D Cell Culture market predicted to reach a value of $3.2 Billion by 2027, researchers globally are realising the growing potential of in vitro applications for drug discovery, predictivity and validation, safety and toxicity. 3D Cell Culture technology promises to offer increased translatability in models and reduce the costly rates of drug attrition in the discovery process -- heralding the next major advance in the discovery of pharmaceuticals.

A 3D cell culture is an artificially created environment in which biological cells are permitted to grow or interact with their surroundings in all three dimensions. Unlike 2D environments (e.g., a Petri dish), a 3D cell culture allows cells in vitro to grow in all directions, similar to how they would in vivo. The crux of 3D cell culture is mimicry – how to best replicate the living environment under experimental conditions, to have the best predictive capabilities when testing drugs.
These spatial and physical aspects in 3D cultures affect the signal transduction from the outside to the inside of cells, and ultimately influence gene expression and cellular behaviour – these are especially important factors to consider when testing a new drug.
 

  • Discuss the capabilities of 3D Cell Culture techniques in enhancing drug discovery with industry experts
  • Pinpoint the hurdles limiting the adoption of translational models
  • Look to the future, assessing the next steps the industry will take in integrating 3D Cell models into drug discovery
     

Key Job Titles include Head of, Director, Manager of...

Complex in vitro models
Cell and molecular science
Disease models
Cell technology
Microphysiological systems
Microfluidics
Toxicology
Stem Cell Sciences
Tissue Engineering
High throughput screening
3D Imaging
 

Previous attendees include:

University College London, GSK; Aixtron Ltd; AstraZeneca; BioLamina AB; Boehringer Ingelheim RCV GmbH & Co KG; Cellbox Solutions GmbH; Cellink; CN Bio Innovations Limited; DMPK; Durham University; Engitix Ltd; Enplas; EPO; European Patent Office; FabRx Ltd; Gadeta B.V.; Genentech; GlaxoSmithKline; GSK; Hitachi High-Technologies Corporation; Institute Pasteur; Lund University; Manchester BIOGEL; Medicines Discovery Catapult; Merck; Merck Healthcare KGaA; Merck KGaA; MHRA; Mimetas; MRC Harwell Institute; MRS Mammalian Genetics; NC3Rs; Newcastle University; Novartis Pharma AG; Novo Nordisk A/S; OpenCell ; Promega UK Ltd; Rousselot - gelatin; Sanofi Pasteur; Sartorius; TreeFrog Therapeutics; Unilever Research Laboratory; University College London; University Of Strathclyde; Viscofan S.A;

 

Workshop programme

8:30 Registration & Coffee

9:00 Opening remarks and introductions

Wendy Rowan

Wendy Rowan, Scientific Director, Novel Human Genetics, GSK
View Bio

9:10 The challenge in drug discovery to reduce clinical attrition

Wendy Rowan

Wendy Rowan, Scientific Director, Novel Human Genetics, GSK
View Bio

  •  Assessing novel techniques in quantitative systems pharmacology to improve translatability
  • Enabling the better prediction of drug efficacy, toxicity, and DMPK
  • Applying 3D cell techniques to minimise costly late-stage clinical trial failures
  • 9:50 The new generation of human translational models for use in drug discovery

    Wendy Rowan

    Wendy Rowan, Scientific Director, Novel Human Genetics, GSK
    View Bio

  • Assessing the limited physiological relevance of 2D cultures
  • Mimicking the natural microenvironments and architectures of functioning tissues
  • Outlining the advantages in 3D culturing for the detection of drug-induced toxicity
     
  • 10:30 Morning Coffee

    11:00 The application and challenges in application of human translational models for drug discovery

    Wendy Rowan

    Wendy Rowan, Scientific Director, Novel Human Genetics, GSK
    View Bio

  • Why the Pharmaceutical Industry has stalled on the uptake of modern translational models
  • Identifying the hurdles facing 3D Cell technologies: Overcoming scalability and reproducibility challenges
     
  • 11:40 Looking to the future

    Wendy Rowan

    Wendy Rowan, Scientific Director, Novel Human Genetics, GSK
    View Bio

  • Evaluating the increased opportunities available through the production of higher-quality preclinical physiological data
  • 12:30 Closing remarks

    Wendy Rowan

    Wendy Rowan, Scientific Director, Novel Human Genetics, GSK
    View Bio

    +

    FEATURED SPEAKERS

    Wendy Rowan

    Wendy Rowan

    Scientific Director, Novel Human Genetics, GSK

    Wendy Rowan

    Scientific Director, Novel Human Genetics, GSK
    Wendy Rowan

    I started my career at Guy’s Hospital Medical School, before transitioning to industry. I have worked for GSK and its legacy companies for over thirty years. Immunology has been a common theme throughout my career, working on aspects of both innate and adaptive immunity in respiratory and autoimmune diseases. In April 2019, I joined the Novel Human Genetics Research Unit with a focus on using genetics to guide target selection for drug discovery. With the aim of reducing attrition in drug discovery, I have a long standing interest in developing and accessing better human translational models for target validation, lead discovery and candidate selection, including safety assessment and PK/PD profiling.

    VENUE

    Copthorne Tara Hotel

    Scarsdale Place, Kensington, London, United Kingdom

    The Copthorne Tara Hotel London Kensington is an elegant contemporary four-star hotel in prestigious Kensington, located just a two minutes walk from High Street Kensington underground station, making exploring easy. The hotel offers well-appointed and comfortable guest rooms combining Standard, Superior and Club accommodation. Club rooms offer iconic views over the city and include Club Lounge access for complimentary breakfast and refreshments. Guests can sample the authentic Singaporean, Malaysian and Chinese cuisine at Bugis Street, traditional pub fare at the Brasserie Restaurant & Bar or relax with a delicious drink at West8 Cocktail Lounge & Bar.

    The Copthorne Tara Hotel boasts 745 square meters of flexible meeting space, consisting of the Shannon Suite and the Liffey Suite, ideal for hosting conferences, weddings and social events. Facilities include access to the business centre 24 hours a day, fully equipped fitness room, gift shop, theatre desk and Bureau de Change. With ample onsite parking outside the London congestion charge zone and excellent transport links via Heathrow Airport, the hotel is the perfect location for business or leisure stays. The hotel is within close proximity to the shops of High Street Kensington, Knightsbridge and Westfield London, Olympia Conference Centre, Royal Albert Hall, Kensington Palace and Hyde Park.

     

    A number of our clients have been approached by third party organisations offering to book hotel rooms. We would advise that you do not book through them as they are not representing the SMi Group. SMi Group books all hotel rooms directly. If you are approached by a third party organisation then please contact us before making any bookings. If you have already booked a hotel room using a third party organisation, we would highly recommend contacting the hotel you were booked into to ensure a booking has been made for you. We would also advise you to please check the terms and conditions of the booking carefully.
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    Copthorne Tara Hotel

    Scarsdale Place
    Kensington
    London W8 5SR
    United Kingdom

    Copthorne Tara Hotel

    The Copthorne Tara Hotel London Kensington is an elegant contemporary four-star hotel in prestigious Kensington, located just a two minutes walk from High Street Kensington underground station, making exploring easy. The hotel offers well-appointed and comfortable guest rooms combining Standard, Superior and Club accommodation. Club rooms offer iconic views over the city and include Club Lounge access for complimentary breakfast and refreshments. Guests can sample the authentic Singaporean, Malaysian and Chinese cuisine at Bugis Street, traditional pub fare at the Brasserie Restaurant & Bar or relax with a delicious drink at West8 Cocktail Lounge & Bar.

    The Copthorne Tara Hotel boasts 745 square meters of flexible meeting space, consisting of the Shannon Suite and the Liffey Suite, ideal for hosting conferences, weddings and social events. Facilities include access to the business centre 24 hours a day, fully equipped fitness room, gift shop, theatre desk and Bureau de Change. With ample onsite parking outside the London congestion charge zone and excellent transport links via Heathrow Airport, the hotel is the perfect location for business or leisure stays. The hotel is within close proximity to the shops of High Street Kensington, Knightsbridge and Westfield London, Olympia Conference Centre, Royal Albert Hall, Kensington Palace and Hyde Park.

     

    HOTEL BOOKING FORM

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    WHAT IS CPD?

    CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

    ‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

    CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

    Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

    CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.

    CPD AND PROFESSIONAL INSTITUTES

    There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

    For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

    CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.

    TYPICAL CPD SCHEMES AND RECORDING OF CPD (CPD points and hours)

    Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

    ‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

    ‘Output’ based schemes are learner centred. They require individuals to set learning goals that align to professional competencies, or personal development objectives. These schemes also list different ways to achieve the learning goals e.g. training courses, seminars or e:learning, which enables an individual to complete their CPD through their preferred mode of learning.

    The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

    As a formal provider of CPD certified activities, SMI Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.

    GLOBAL CPD

    Increasingly, international and emerging markets are ‘professionalising’ their workforces and looking to the UK to benchmark educational standards. The undertaking of CPD is now increasingly expected of any individual employed within today’s global marketplace.

    CPD Certificates

    We can provide a certificate for all our accredited events. To request a CPD certificate for a conference , workshop, master classes you have attended please email events@smi-online.co.uk

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